Welcome to the Computational Comparative Genomics Lab led by
Department of Bioengineering
Institute for Genomic Biology
University of Illinois at Urbana-Champaign.
The success of the Human Genome Project has ushered in a new era in which
biology has become an information science.
More recently, the rapid advancement in ultra high-throughput DNA sequencing
technologies underlines the urgent need for more innovative computational
research in modern biology, for generating, analyzing, and understanding
massive amount of genomic data to develop and evaluate biological hypotheses.
Our long-term research goal is to understand how phenotype (at the cellular and organism levels)
is generated from genotype and to shed new light on disease mechanisms, such as cancer.
Our interdisciplinary work combines genomics,
computational innovation, engineering principles, and medical sciences.
We develop novel computational methods to explore the human genome,
integrating comparative genomics data to elucidate cross-species
differences and within-species variation and their associations with disease.
We develop new systems biology approaches to identifying key genetic
variants in cancer development and progression using
high-throughput next-generation sequencing technologies.
[Postdoc Position Available]
[PhD Student Position Available]
09/03/2013. IGB GNDP theme received a $3M grant from the Simons Foundation.
07/30/2013. Collaboration with Gene Robinson
gets published as a cover story
05/24/2013. We have a 3-year NSF
ABI Innovation grant that has been recommended for funding.
05/16/2013. Collaboration with Olgica Milenkovic
and Huimin Zhao
01/10/2013. RACA is published in PNAS
05/14/2012. We received a 2-year grant from the Interdisciplinary Innovation Initiative (In3
05/11/2012. We received a Junior Cancer Investigator Pilot grant from UI Cancer Center
to study prostate cancer.
02/21/2012. We received an R21 grant from NIH
to study conserved non-coding elements.
02/01/2012. Jaebum joined Konkuk University
(Seoul, Korea) as an Assistant Professor.
12/19/2011. Yang's TrueSight paper has been accepted by
12/01/2011. Jian is named one of "Tomorrow's PIs"
by Genome Technology
05/13/2011. We received Arnold O. Beckman Award from the University to study genome aberration in cancer.
03/12/2011. Peter's work has been selected for oral presentation at the
2011 Undergrad Research Symposium
12/06/2010. Jaebum's PSAR paper has been accepted by
11/16/2010. We will receive
NSF CAREER Award
to study large-scale genomic changes in mammalian genomes.
08/16/2009. We received a faculty fellowship from NCSA
08/16/2009. Our lab started officially.